Every human and every system has its own way of reaction, the way a dose feels for one person, can feel  completely different for the next. Everything comes back to your breath and ability to find your inner  calm. If you are experiencing effects that are making you uncomfortable, take a moment to get  comfortable, and understand that it is all temporary. Naturally, when the body is undergoing elements of  sensation that it is not familiar with, a common instinct is resistance. It is important to trust your inner  judgement, while also keeping in mind that at times, discomfort is a part of the process. Drink some water or tea, make your spot comfortable, and find comfort in the thought that it will not hurt you, and the only thing in full control is you. Focus on your breaths, and let it flow.