Psilocybin acts as a central nervous system stimulant, therefore the rise in stimulation could make it very difficult to sleep, potentially resulting in insomnia if taken at night. Taking a microdose in the morning allows more time for effects to be felt throughout common acts of the day, in turn, giving you a clearer idea of what microdosing may enhance for you. Although, some have recounted that a decrease in anxiety has allotted an easier time relaxing, and furthermore resulting in a better night’s sleep. If you decide to try microdosing in the evening, we recommend trying on a night where you are able to sleep in on the following morning, in case you have adverse effects.